AZT is a reverse transcriptase inhibitor. How does this drug prevent the replication of a retrovirus

Answers

Answer 1

Answer:

AZT is a thymidine analog

Explanation:

Azidothymidine (AZT) is an antiviral drug used for the treatment of the Human immunodeficiency virus infection (HIV/AIDS) by preventing the transmission of HIV from infected cells. AZT is capable of suppressing the activity of the enzyme reverse transcriptase of the retroviral HIV genome, which enables it to copy RNA into DNA. In infected cells, this double-stranded DNA is integrated into the host genome which is then instructed to produce identical HIV copies. AZT is a thymidine analog that is incorporated into DNA and thus interferes with DNA synthesis, thereby inhibiting cell proliferation.


Related Questions

what is the feature of the eye and it's parts​

Answers

Answer:

1. Cornea

2. Pupil

3. Iris

4. Conjunctiva Glands

5. Lacrimal Glands

Answer:

The cornea, a clear window at the front of the eye, covers the iris and the pupil. A clear lens, located behind the pupil, acts like a camera lens by focusing light onto the retina at the back of the eye. The retina is a light-sensitive inner lining at the back of the eye.

make me brainliest

Which is incorrect descriptions of the genetic event initiated by the HIV reverse transcriptase (RT) upon the HIV infection?
a. RT catalyzes initial synthesis of ssDNA using viral genomic RNA as the template.
b. The first RNA template is degraded after ssDNA synthesis.
c. The whole process is completed after synthesis of dsDNA.
d. tRNAs are adopted as the first primers.
e. None of these

Answers

Answer:

e. None of these

Explanation:

The immune deficiency viruses (HIV) are retroviruses that use a reverse transcriptase (RT) enzyme to produce a single-stranded DNA (ssDNA) from an RNA template. The reverse transcription allows retroviruses to replicate their genetic material, which is integrated into the host's genome as a double-stranded linear DNA molecule in a similar way to the mechanism of insertion used by endogenous retrotransposons. The synthesis of DNA is started by cellular tRNAs (tRNA3Lys) that are packaged into the virion. After reverse transcription, the HIV DNA enters the nucleus of CD4 immune cells (also known as CD4+ T cells), and then it integrates into the genome to coopt the host's cell machinery for its own replication.

2x - 5 = 7
slove for x

Answers

2x-5=7

2x=7+5

2x=12

x=12/2

x=6

_______


reptilesimprovements over amphibians​

Answers

The person above me is correct

What are the
traditional
circulatory
endpoints of
resuscitation
in shock?​

Answers

Explanation:

traditional circulatory endpoints of resuscitation in shock include hypertension,tachycardia,decreased mentation and urine output

Aquatic organisms in coastal areas face a variety of predators on land and in the water and air. Which ocean process exposes the coastal aquatic organisms to land-based predators? a. Changing wind patterns alter the ocean currents, changing tide levels. b. Daily tidal patterns leave areas exposed to the land for part of the day. c. The constant wave action generates nutrients that attract predators. d. The ocean conveyor belt raises and lowers the water levels on the coasts.

Answers

Answer:

b

Explanation:

The correct answer as to the ocean process that exposes the coastal organisms to land-based predators would be the daily tidal patterns that leave the coastal area exposed to the land for a part of the day.

Some parts of the coastal areas become exposed to land during certain periods of the day as a result of tidal waves. When this happens, the aquatic organisms occupying these coastal areas become temporarily exposed to land predators who hunt and kill them for food.

Therefore, the correct option is b.

The original name for Asian Homo erectus was Group of answer choices Homo rudolfensis. Australopithecus. Paranthropus. Pithecanthropus.

Answers

Answer: Pithecanthropus erectus.

Explanation:

Between 1891 and 1892 Eugène Dubois believed he had found the "missing link", hypothesized by Ernst Haeckel, when he discovered some loose teeth, a skull cap and a femur - very similar to that of modern man - in the excavations he was carrying out in Trinil, located on the island of Java, Indonesia. Homo erectus erectus was the first specimen of Homo erectus to be discovered.  Dubois first named it Anthropopithecus erectus and then renamed it Pithecanthropus erectus. The name Homo erectus means in Latin "erect man", wich means, "standing man", whereas Pithecantropus erectus means "standing ape-man".

So, Dubois published these findings as Pithecanthropus erectus in 1894, more popularly known as "Java Man" or "Trinil Man". In the 1930s the German palaeontologist Ralpf von Koenigswald obtained new fossils, both from Trinil and from new locations such as Sangiran and in 1938 von Koenigswald identified a magnificent Sangiran skull as "Pithecanthropus". It was not until 1940 that Mayr attributed all these remains to the genus Homo (Homo erectus erectus).

Which of the following pairs of organisms
would have the MOST SIMILAR niche in
their environments.
Zebra and Lion
Squirrel and Chipmunk
Robin and Bald Eagle
Oak Tree and Mushroom

Answers

Answer:

Squirrel and Chipmunk

Answer:

C. a lion hunting for a zebra in the grassland  

Explanation:

E2023

Please add the missing term:
Species -> Population -> Community
-> Ecosystem -> Biome ->
A. Ecology
B. Life Bubble
C. Hydrosphere
D. Biosphere
Copyright 2003 - 2021 Acellus Corporational

Answers

Answer:

Biosphere hope its a good one

Which of the following is true about the speed of light?
O it is a constant when the light is traveling in a vacuum.
O It speeds up or slows down depending on the observer.
O It is slowest in a vacuum.
O lt varies depending on the color of the light.

Answers

Answer:

It is a constant when the light is traveling in a vacuum.

Explanation:

In ______, Gorter and Grendel extract lipids from blood cells. After evaluating them, they propose membranes are made of a ____________.

Answers

Answer:

The correct answer would be - 1925, phospholipid bilayer.

Explanation:

Gorter and Grendel performed an experiment in 1925 to extract lipids from blood cell and after extracting the protein they evaluated red blood cell membrane.

They found out that plasma membrane have two lipid layer and these lipids are made of phospholipids. Phospholipids are phosphate group that are attached with the lipid molecule.

Thus, the correct answer would be - 1925, phospholipid bilayer.

General and Specific knowledge example

Answers

The sky is blue, Planes travel because of the pressure under the wings

GENERAL: the sky is blue SPECIFIC: Planes travel because of the pressure under the wings

When neuroscientists employ the term "nucleus", they are usually referring to:_____.
​a. a cluster of glial cells in the dorsal-medial CNS.
​b. a neural unit composed of anatomically and functionally related neurons.
​c. a group of homologous ganglia located either in the cortex or in the cerebellum.
​d. cognitively synchronized clusters of apical dendrites anywhere in the PNS.

Answers

Answer:

B. A neural unit composed of anatomically and functionally related neurons.

If you insert a gene from bacteria into a mouse genome, then which terms best explains what you just made?

Answers

Answer:

a transgenic animal

Explanation:

three (3) advantages of using a resource person in handling the First Aid lesson.

Answers

Answer:

Advantages of resource person in handling the first aid lesson are as follows:

He is an expert who share important points during first aid and prevents any mishappening.They also provide assistance to the community member and provide social audits in villages.A resource person can share extreme difficult cases of injuries and will introduce new methods to adopt first aid in those conditions.

_is a molecule that directs all of a cells activities

Answers

Answer:

[tex]\boxed{\mathrm{Nucleus}}[/tex]

Explanation:

The nucleus directs all cellular activities. The nucleus also contains genetic material of eukaryotic organisms.

The vector allows for protein expression in E. coli.

Briefly explain the role of the following elements in the context of gene expression and protein production:

1- LacP:

2- LacO:

3- LacZa:

4-Briefly explain and indicate what is required for high expression in E. coli in this context..

The vector also contains other important elements. Explain their role:

5- AmpR:

6- ori:

Answers

Answer:

1. Lac P or the promoter is the binding site for RNA polymerase, situated just upstream to the gene.  

2. Lac O or operator is a sequence situated just downstream to the sequence of the promoter at which binding of the repressor protein is done and ceases RNA polymerase enzyme from binding.  

3. Lac Z refers to the gene that encodes for protein beta-galactosidase, which further results in the formation of glucose and galactose from lactose.  

4. For high expression in E.coli IPTG is required. It attaches with the lac repressor and discharges the tetrameric repressor from the lac operator in an allosteric fashion, thus, permitting gene transcription in the lac operon.  

5. AmpR is also known as the ampicillin-resistant gene, which is utilized as a selective marker for selection against ampicillin antibiotic.  

6. Ori or the origin of replication refers to the sequence of the genome, which is accountable for the initiation of replication.  

Tell me three things that you know about controlling microbial growth - think about how you handle certain foods in you home. Why is it so important to learn about how we can control microbes

Answers

1. Cooking food properly. Undercooked foods may still contain microorganisms that are harmful.

2. washing raw foods properly. It can remove thermophilic microorganisms which can't be inhibited by temperature.

3. Hands should be clean. Handling affects the most.

Its important to learn about controlling microbes because

microbes are everywhere and many are really harmful for other living beings. so,

•To be safe from life-threatning diseases.

Which medical conditions are associated with large amounts of fat and sugar in your diet? Select three options.

Answers

Answer:

gall bladder disease

hypertension

osteoarthritis

Answer:

diabetes

heart disease

obesity

Explanation:

When discussing magnetic fields we could say that
metals can become magnetic if they have many spinning electrons that create magnetic fields
O metals are magnets because they have more electrons than non-magnetic materials
O non-paired electrons spin in opposite directions creating a magnetic field
the spinning electrons in some atoms pair up and create a magnetic field

Answers

Answer:

Explanation:

metal can become magnetic if they have many spinning electron. When the majority of atoms spin in the same direction the strong magnetic field is produced the direction of electron spin determine the direction of magnetic field

When the body cells are hypotonic to the blood plasma, water will move from intracellular fluid to extracellular fluid.
A. True
B. False

Answers

Answer:

True

Explanation:

Lactose (milk sugar) is a carbohydrate that is formed by combining galactose and glucose. Which term best describes this molecule?

Answers

Answer:

disaccharide

Explanation:

A disaccharide is a form of sugar that is made up of the combination of two other sugar molecules that are simple. They possess the property to dissolve easily in water. The process that occurs to join the two simple sugars includes the removal of water from the molecules. Sucrose, lactose, and maltose are the three disaccharides.

Answer:

disaccharide

Explanation:

A disaccharide is a form of sugar that is made up of the combination of two other sugar molecules that are simple. They possess the property to dissolve easily in water. The process that occurs to join the two simple sugars includes the removal of water from the molecules. Sucrose, lactose, and maltose are the three disaccharides.

The dark bands seen under the microscope in a skeletal muscle fiber are concentrations of actin protein called l-bands . It is true or false.

Answers

Answer:

it is false

Explanation:

it appears as light bands under microscope

Answer:

false

Explanation:

because dark band seen under the microscope in a skeletal muscle fiber are concentration of actin protein  are known as A bands because they are anisotropic when viewed with polarized light

Describe your plan to preserve the biodiversity of the town's lake. Make sure to include the materials that you would need for your plan to work and how you would scale it up to test it.

Answers

Answer:

10 Ways to Protect and Conserve Biodiversity

Government legislation.

Nature preserves.

Reducing invasive species.

Habitat restoration.

Captive breeding and seed banks.

Research.

Reduce climate change.

Purchase sustainable products.

What does cyclical mean

Answers

Cyclical means occurring in cycles technically meaning reoccurring.

Anyone know this??? Help!!!
Devise an experiment to test the effect of pH on the activity of biological washing powder

Answers

Answer:

I think you are nepali yeah but I don't have your question ❓ answer

Gene X always produces the same mRNA (one splice form) and the same protein in all cells in which it is expressed. The same amounts of gene X mRNA and protein are present in brain, kidney, and heart cells. However, the activity associated with the protein is present only in the heart. Which of the following are possible explanations?

a. A splicing factor necessary for removing all of the primary transcript's introns is present only in the heart.
b. A splicing factor necessary for removing all of the primary transcript's introns is present only in the brain and kidney.
c. Protein X is phosphorylated only in the heart.
d. Protein X is phosphorylated only in the brain and kidney.

Answers

There are two explanations for this phenomenon: phosphorylation of the protein X in the heart activates its function (Option C) or phosphorylation of the protein X in the kidney and the brain deactivates its function (Option D). Therefore, both Option C and Option D are correct.

Phosphorylation is a posttranslational protein modification that is capable of activating or deactivating protein function.

Phosphorylation alters the three-dimensional structure of a protein, thereby modifying its function (i.e., activate or deactivate the target protein).

Phosphorylation occurs at specific amino acids (e.g., serine and threonine residues) of the target protein.

Moreover, mRNA splicing (RNA processing) occurs before the protein state, it is a transcriptional process. This process consists in removing the non-coding regions or 'introns' from pre-mRNA and subsequent joining protein-coding regions or 'exons' to enable the translation of the mRNA into a protein.

In consequence, in this case, it is possible that 1-phosphorylation of the protein X in the heart activates its function, or 2-phosphorylation of the protein X in the kidney and the brain deactivates its function. Therefore, both Option C and Option D are correct.

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PLEASE ITS URGENT!
Can someone help me name them!

Answers

Answer:

i filled the thing out for you. i didnt know what grade you were in so i just put the cell names in.

Explanation:

what is sexual reproduction

Answers

Answer:

See explanation below...

Explanation:

Sexual reproduction is a type of reproduction that involves a complex life cycle in which a gamete with a single set of chromosomes combines with another to produce an organism composed of cells with two sets of chromosomes.

Best Regards!

Answer:

the production of new living organisms by combining genetic information from two individuals of different types (sexes). In most higher organisms, one sex (male) produces a small motile gamete which travels to fuse with a larger stationary gamete produced by the other (female).

Plaque formation in virus is done for :
a) Isolation and typing of virus
b) Cloning seperation of specific of virus
c) Determining infectivity of virus
d) Accessing multiplication of virus​

Answers

Answer:

I think the answer is determining infectivity of a virus

Explanation:

hope that it will help you

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