DNA sequences can act as "tape measures of evolution". Scientists analyzing the human genome sequence were surprised to find that some of the regions of the human genome that are most highly conserved (similar to comparable regions in other species) don't code for proteins. What is a possible explanation for this observation? EVOLUTION CONNECTION sequences can act as "tape measures of evolution". Scientists analyzing the human genome sequence were surprised to find that some of the regions of the human genome that are most highly conserved (similar to comparable regions in other species) don't code for proteins. What is a possible explanation for this observation?

Answers

Answer 1

Answer:

Non-coding DNA regions play important roles in regulating transcriptional activity by encoding different types of non-coding RNAs (ncRNAs), acting as scaffold attachment regions, acting as enhancer specific regions, etc.

Explanation:

Historically, it had been believed that non-coding DNA sequences were 'junk DNA' since they don't encode for proteins (beyond the sequences that are transcribed into functional non-coding RNAs, i.e., transfer RNA and ribosomal RNA). However, in the last years, it has been shown that non-coding DNA sequences play critical roles in regulating gene expression and genome function. For example, evolutionary conserved non-coding RNAs (ncRNAs) with regulatory roles on gene expression such as, for example, long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) have been mapped in non-coding DNA sequences, thereby evidencing the functional significance of these regions. In consequence, the conservative nature of certain non-coding DNA sequences evidence that mutations in such regions may have significant deleterious effects, and thereby they could have a negative impact on the fitness of the individual.


Related Questions

Let's suppose you were interested in developing drugs to prevent epigenetic changes that may contribute to cancer. What cellular proteins would be the target of your drugs?

Answers

Answer:

Potential targets:

1- DNA methyltransferases

2- Chromatin modifiers such as histone acetyltransferases, histone deacetylases, histone methyltransferases, etc.

3- Components of the RNA interference (RNAi) machinery such as Dicer, Argonaute, etc.

Explanation:

Epigenetics can be defined as the study of any heritable change in the phenotype that does not involve modifications in the DNA sequence. Epigenetic mechanisms can be classified into three major types: 1-DNA methylation, 2-histone modifications (e.g., acetylation, methylation, phosphorylation, etc), and 3-regulatory non-coding RNAs (e.g., miRNAs, lncRNAs, siRNAs, etc) that modulate target gene expression via the RNA interference pathway. There are different types of proteins that are involved in these complex epigenetic mechanisms, and those cited above represent only some examples that can be used as therapeutic targets.

How are the enzymes that nerve cells produce different from the enzymes that blood cells produce? A. The molecules that nerve cells digest are more complex than those digested by blood cells. B. The genes that are activated in nerve cells are different from those activated in blood cells. C. Nerve cells contain more ribosomes than blood cells. D. Nerve cells contain more mitochondria than blood cells.

Answers

Red blood cells carry a specific type of protein, called hemoglobin, which is able to bind oxygen and release it in other tissues. A nerve cell doesn't have this protein because it doesn't need to bind oxygen. Instead, the nerve cell uses other proteins that help it transmit signals to other cells.

How do
you think humans can impact the
biosphere by affecting the biogeochemical
cycles?

Answers

Answer:

hope this will help u

Explanation:

Biogeochemical Cycles

Human activities have greatly increased carbon dioxide levels in the atmosphere and nitrogen levels in the biosphere. Altered biogeochemical cycles combined with climate change increase the vulnerability of biodiversity, food security, human health, and water quality to a changing climate.

Explore interactions between climate change and biogeochemical cycles.

Answer:

Human activities

moreover, biogeochemical cycles combined with climate change increase the vulnerability of biodiversity, food security, human health, and water quality to a changing climate.

What is the role of DNA polymerase in DNA replication?

A. It ties the chunks of DNA together.
B. It creates the replication fork.
C. It checks the DNA for errors.
D. It breaks apart the bases.

Answers

Answer: it checks the DNA for errors

Explanation:

Just took test

Answer:

A. ties chunks of dna together, took the test

Explanation:

Determine the identity of an atom

Answers

Answer:

The number of protons in one atom of an element determines the atoms identity.

Homeostasis: Response to Stimuli
From the examples below, select the examples of cells or organisms responding to stimuli in order to maintain homeostasis.
1.)A plant bending toward a light source
2.)A cell bursting because it takes up too much water
3.)A person shivering when their body temperature is low
4.)A unicellular organism beating microscopic hairs to escape a chemical pollutant in its environment
5.)A cell dying due to a chemical poison
6.)An animal growing larger
7.)Ants moving within their mounds depending upon the time of day
8.)Iguanas laying in the sunlight if their body temperature is low
9.)Birds migrating when seasons change
10.)A person or animal getting sick because of infectious bacteria
part2 fill in the blank
A state of biological balance, or ____________ , is important for the survival of individual cells and ____________ alike.
Physiological factors such as ____________ , water levels, and pH must remain within a certain ____________ for cells and organisms to remain healthy and functional.
Regulation of the ____________ environment of cells and organisms is carried out through ____________ and other control ____________ .
choice of words:
location
external
hormones
mechanism
homeostasis
internal
groups
feedback
oganisms
temperature
range

Answers

Answer:

3.)A person shivering when their body temperature is low.

7.)Ants moving within their mounds depending upon the time of day

1-A plant bending toward a light source.

.-Iguanas laying in the sunlight if their body temperature is low.

.-A unicellular organism beating microscopic hairs to escape a chemical pollutant in its environment

.-Birds migrating when seasons change.

The maintenance of relatively constant internal environment of an organism is called  Homeostasis.It is an automatic regulations of the body systems and organs controlled by the brain and some receptors, specific for certain body fluctuations.E.g Thermoreceptors Chemoreceptors etc.

The fluctuations in the body internal systems must be controlled within a narrow limits, for existence of living organism.The brain receives inputs from the receptors, and the outputs from the brain ensures the  homeostatic control.

The above examples are typical homeostatic responses by the organisms involved, because the inputs from the receptors  send signals to the brain ,and the organisms  responded to these with the example above.

Explanation:

Two different groups of scientists studying a rare trait in ground squirrels report very different heritabilities. What factors influencing heritability values make it possible for both conclusions to be correct?

Answers

Answer:

It is a trait highly influenced by environmental factors (i.e., it has low heritability)

Explanation:

In population genetics, heritability is a statistical measure to estimate the proportion of the phenotype variation of a given trait which can be explained by hereditable genetic factors. The heritability of a trait is influenced by environmental factors, genetic factors (e.g., allele frequencies, number of genes involved in trait variation, recombination rate, etc), and the interaction between genetic and environmental factors. A low heritability value suggests that most of the variation is not genetic (i.e., due to environmental factors), while a high heritability value suggests that almost all of the variability in a trait is due to genetic factors.

particles is found in the nucleus of an atom

Answers

Answer:

protons and neutrons

Explanation:

Protons and neutrons have a positive and neutral charge, respectively. They are in the nucleus, while the negative electrons orbit the nucleus.

Answer:

Protons, neutrons, electrons

Explanation:

If you're asking about subatomic particles.

How does Nitrogen get from the atmosphere to the soil?

Answers

Answer:

Plants get their nitrogen indirectly from the air via microorganisms in the soil and in certain plant roots.

Answer:

Microorganisms and certain plant roots in the soil

Explanation:

"Plants get the nitrogen that they need from the soil, where it's already been fixed by bacteria and archaea. Bacteria and archaea in the soil and in the roots of some plants have the ability to convert molecular nitrogen from the air (N2) to ammonia (NH3)... Such organisms are called "diazotrophs". From here, various microorganisms convert ammonia to other nitrogen compounds that are easier for plants to use. In this way, plants get their nitrogen indirectly from the air via microorganisms in the soil and in certain plant roots."

I hope this helps...

What molecule, when linked
with others, creates a single link
in the DNA chain?

Answers

Answer:Figure 4: Double-stranded DNA consists of two polynucleotide chains whose nitrogenous bases are connected by hydrogen bonds.

Explanation::))))))))))))))))))))))

what is the last thing that happens when a cell divides to produce two new identical cells

Answers

Answer:

The last phase of cell division is cytokinesis. In this phase the cytoplasm of parent cell divides in to two cells called as daughter cells. It occurs during late stages of nuclear division.

The visible change of cytokinesis in an animal cell can be observed as formation of Furrow or Pucker on the cell surface.

When you are sitting in a bath, are your skin cells in a hypertonic or hypotonic solution?

Answers

Answer:

hypotonic

Explanation:

In science, which of the following best describes the scientific term
theory? *
A) An educated guess
B) An idea with lots of evidence to support it
C) possible idea that needs more evidence to be real science
D) An undisputed law that will not change.

PLEASE ANSWER!!!!!!!

Answers

Answer:

here's your answer

Explanation:

b) an idea with lots of evidence to support it .

In science, the word theory refers to a comprehensive explanation of an important feature of nature that is supported by many facts gathered over time. Theories also allow scientists to make predictions about as yet unobserved phenomena.

Explain what would happen if the body's kidneys failed?

A. The body will not be able to produce enough blood.
B. The body will not be able get rid of waste products made by cells.
C. The body will not get sufficient amount of clean water.
D. The body will not be able to dispose of carbon dioxide in the blood.

Answers

Answer:

b:) the body will not be able to get rid of waste products made by cells

Explanation:

Budding is a type of asexual reproduction. Which of the following is an disadvantage for asexual reproduction?

Answers

Disadvantages of asexual reproduction include: offspring compete for food and space, extreme temperatures can wipe out entire colonies, negative mutations can destroy many offspring.

Which type of rock does B represent?

Group of answer choices

Answers

I thing it is volcanic rock

A plant that was grown in the dark continuously would: ________.

a. not be able to take in CO2 without sunlight.
b. remain healthy because plants have stored materials in their roots that can provide what the Calvin cycle needs.
c. not be able to split water to provide NADH.
d. continue to photosynthesize because to in carbon dioxide, the only outside input to the Calvin cycle, does not require sunlight.

Answers

Answer:

c. not be able to split water to provide NADH.

Explanation:

Photosynthesis, which is the process by which plant species obtain their energy, occurs in two stages viz: light dependent phase and light independent phase. The light dependent phase of photosynthesis requires the energy from sunlight, which is captured by the chlorophyll pigments in the leaves of the plant.

The light energy captured by the chlorophyll is used to split water molecule in a process called PHOTOLYSIS OF WATER. Overall, ATP and NADH (electron donor) are products of the light dependent stage, which enters the next stage to complete the photosynthetic process.

Therefore, a plant that was grown in the dark i.e. no access to light, continuously would not be able to capture light energy and hence not be able to split water to provide NADH.

A plant that was grown in the dark spontaneously would not possess the tendency to split water to provide NADH.

What is photolysis of water?

The process by which the species of plant attain their energy, that is, photosynthesis, takes place in two stages:

Light independent phaseLight dependent phase

In the light dependent phase, energy is needed from sunlight, and is captivated by the chlorophyll pigments present in the leaves of the plant. This energy from the light is used to split the molecule of water by a process known as photolysis of water.

The products of the light dependent stage is ATP and NADH that enters the next phase to complete the process of photosynthesis. Therefore, a plant, which was grown in the dark, that is, having no accessibility to light, would not possess the tendency to captivate the energy from the sunlight and thus would fail to split the molecule of water to provide NADH.

Thus, the correct answer is option c.

Find out more information about the photolysis of water here:

https://brainly.com/question/13984369

what does carbon footprint mean???

Answers

Answer:

A carbon footprint is the total greenhouse gas emissions caused by an individual, event, organization, service, or product, expressed as carbon dioxide equivalent.

Explanation:

Answer:

The amount of carbon dioxide a person produces

Explanation:

a. What is the major evolutionary advantage to producing an amnion?
b. What does that mean for embryonic development for the animal phylum as compared to the animal phyla?

Answers

WHAT IS THE MAJOR EVOLUTIONARY ADVANTAGE TO PRODUCING AN AMNION?

The main evolutionary advantage of producing an amnion is that the embryos of the amniotic membrane,the amniotes are made available with their own aquatic environment,this in-turn resulted to a lesser dependence on water for it's maturation and development therefore allowing or giving room for the amniotes to branch towards environments that are drier.

WHAT FOES THAT MEAN GOR EMBRYONIC DEVELOPMENT OF THE ANIMAL PHYLUM AS COMPARED TO THE ANIMAL PHYLA?

The embryonic development of animal phylum is also known as embryogenesis.

It is the development of the embryo from the point of fertilization of an egg,(the ovum) by a sperm cell ,this makes the fertilized egg a diploid cell otherwise known as a zygote.

This zygote undergoes mitosis,a mitotic division known as cleavage and a differentiation resulting in a multicellular embryo.

This embryonic development of animal phylum comprises of 36 animal phyla.

1. Does a scientific theory ever become a law? Explain
the difference between scientific theory and law.

Answers

Answer:

a theory cannot become a law

Explanation:

the difference between a scientific theory and a scientific law because a theory is an in depth explanation of an observed phenomenon. a law is a statement about an observed phenomenon or an unifying concept (i.e.: newtons law or gravity - no explanation on how it works or what it is just that it exists.)

No a theory can not be a law

Plz help I’ll mark brainliest

Answers

Answer:

C. The study of the interaction between living and nonliving factors in an environment

Explanation:

Ecology is the study of both living and nonliving things in an environment, the only answer that relates to this in significance is C.

The decimal reduction time (DRT) to kill 90% of cell present for autoclaving a culture is 1.5 minutes. How long would it take to kill all the cells if 106 cells were present? What would happen if you stopped the heating process at 9 minutes?

Answers

Answer:

10.5minutes

Explanation:

DRT = 90%

Cells present = 10^6

Autoclaving = 1.5 minutes

Solution:

10^6(1.5)10^5(1.5)10^4(1.5)10^3(1.5)10^2(1.5)10^1(1.5)10^0(1.5)0=10.5

it would take it approximately 10.5 minutes to kill 10^6 of the cells.

If i should stop the heating process at 9 minutes this would have effect on some of the microbes as they are still present with 1 bacterium left which makes it not efficient.

XR

Which of the three traits considered in this film (bipedality, extensive tool use, and large brains) were present in the 3.2-million-year-old Australopithecus fossil (Lucy)?.

Answers

Answer:

The bipedality

Explanation:

One of the things the discovered fossil signified was that human bipedality was more ancient than the large brain size because Lucy actually had a small skull which could indirectly be translated to small brain size.

NOTE: Bipedality can be described to mean the ability of an organism to move about with two legs. Hence, it must have been discovered that Lucy had two legs.

Can you read this??


Dndkfrjjdfjjd

Answers

Answer:

I can't read the picture because it's too pixelated, but "Dndkfrjjdfjjd"

clearly means "Da National Day Known For ReJoicing Joe's Dad For Joyous Jiving Dogs".

35 points please help science biology

Answers

Euglena are unicellular organisms classified into the Kingdom Protista, and the Phylum Euglenophyte. All euglena have chloroplasts and can make their own food by photosynthesis. They are not completely autotrophic though, euglena can also absorb food from their environment; euglena usually live in quiet ponds or puddles.

Euglena move by a flagellum (plural ‚ flagella), which is a long whip-like structure that acts like a little motor. The flagellum is located on the anterior (front) end, and twirls in such a way as to pull the cell through the water. It is attached at an inward pocket called the reservoir. Color the reservoir grey and the flagellum black.

The Euglena is unique in that it is both heterotrophic (must consume food) and autotrophic (can make its own food). Chloroplasts within the euglena trap sunlight that is used for photosynthesis, and can be seen as several rod like structures throughout the cell. Color the chloroplasts green. Euglena also have an eyespot at the anterior end that detects light, it can be seen near the reservoir. This helps the euglena find bright areas to gather sunlight to make their food. Color the eyespot red.Euglena can also gain nutrients by absorbing them across their cell membrane, hence they become heterotrophic when light is not available, and they cannot photosynthesize.

The euglena has a stiff pellicle outside the cell membrane that helps it keep its shape, though the pellicle is somewhat flexible and some euglena can be observed scrunching up and moving in an inchworm type fashion. Color the pellicle blue.

In the center of the cell is the nucleus, which contains the cell's DNA and controls the cell's activities. The nucleolus can be seen within the nucleus. Color the nucleus purple, and the nucleolus pink.

The interior of the cell contains a jelly-like fluid substance called cytoplasm. Color the cytoplasm light yellow. Toward the posterior of the cell is a star-like structure: the contractile vacuole. This organelle helps the cell remove excess water, and without it the euglena could take in some much water due to osmosis that the cell would explode. Color the contractile vacuole orange.

(Q005) Humans are unusual because our cultural practices can actually change our environmental circumstances. We can change the environment in which natural selection acts on our traits. Describe how this process has played out in the evolution of adult lactose tolerance. Describe how this process has played out in the maintenance of the sickle-cell trait. Can you hypothesize any similar situations where our future evolution may be influenced by cultural practices we have today?

Answers

Answer:

sickle cell disease or sickle cell disease is about the inheritance of metaplastic cells or cells that do not respect normal cell morphology from the mother or father to a child.

This is not associated with cultures, instead lactose tolerance is.

Explanation:

Lactose tolerance is basically an adaptation of the body in those humans who continue to drink milk throughout their lives, once the growth stage is over, milk should be suspended, although some continue to consume it and lactase continues to be encoded and expressed.

Some people for cultural reasons or environmentalist lifestyles do not drink animal milk, but rather vegetable milk.

The process of photosynthesis requires the starting materials

Answers

Answer:

Carbon Dioxide, Water, and sunlight

Explanation:

Answer:CO2 and H2O

Explanation:

Help me guys!! (Giving brainliest)

Answers

Answer: C

Explanation:

C because the cell membrane is semi permeable which means only certain substances can enter and exit.

Why do lunar and solar eclipses not happen every month?

Eclipses only occur during full and new moons.
Earth rotates around its axis faster than the moon.
The moon and Earth only travel through the penumbras.
The moon’s axis does not always align with Earth’s shadow.

Answers

Answer:

Eclipses only occur during full and new moons. Earth rotates around its axis faster than the moon. ... The moon's axis does not always align with Earth's shadow.

Explanation:

Answer:

The moon's axis does not always align with Earth's shadow.

Explanation:

The Earth goes around the Sun, while the moon goes around the Earth, so all of them lining up exactly doesn't happen that much. I also jus got it right.

Do the same mechanisms that govern gene expression operate in bacterial cells and eukaryotic cells? Explain your answer.

Answers

Answer:

in prokaryotic cells, the control of gene expression is mostly at the transcriptional level. ... Eukaryotic gene expression is regulated during transcription and RNA processing, which take place in the nucleus, and during protein translation, which takes place in the cytoplasm.

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