Phase 1 TRANSCEND CLL 004 study of lisocabtagene maraleucel in patients with relapsed/refractory CLL or SLL

Answers

Answer 1

TRANSCEND CLL 004 is a clinical trial that assesses a type of CAR T-cell therapy in patients suffering relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma.

What is CAR T-cell therapy?

The chimeric antigen receptor (CAR) T-cell therapy is a gene therapy based on genetic engineering to produce T cells that are able to target specific antigens.

The chimeric antigen receptor (CAR) T-cell therapy may result very useful to kill specific cancer cells.

In conclusion, TRANSCEND CLL 004 is a clinical trial that assesses a type of CAR T-cell therapy in patients suffering relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma.

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Related Questions

What is true if takt time is 30 seconds and cycle time is 40 seconds

Answers

If takt time is 30 seconds and cycle time is 40 seconds then all demand is not satisfied.

What is Cycle Time?

Cycle Time is known to be the amount of time that a group of people or a team can spends if they are said to be working on making an item, up till the product is ready for shipment.

Note that It is the time it that it serves or takes to complete one task and as such, If takt time is 30 seconds and cycle time is 40 seconds then all demand is not satisfied.

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Which of the following is an equity security

Answers

Common shares is an example of equity security.

What is an equity security?

This is the term that is used to refer to the ownership of the interests by the given shareholders of a company.

It talks about the shares that are held by the entity in the company or the partnership. Equity shares are the claims that a person may have to the net assets that are owned by a business.

It is a significant aspect of the investment portfolios of people and organizations that may invest in other companies. Common shares are the most common type. Although this does not include the names of the share holders in the business.

These are the other types of equity security

The Common shares.Callable  shares.Puttable  shares.Preference shares.Cumulative preference shares.

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Which of the following are common causes of breaches

Answers

Weak and stolen credentials.
Application vulnerabilities.
Malware.
Malicious insiders.
Insider error.
Secure your organisation with penetration testing.

ddNTPs and dNTPs differ in which portion of the nucleotide

Answers

The portion of the nucleotide in which ddNTPs and dNTPs differ is known as deoxyribose sugar.

What is a nucleotide?

A nucleotide is the subunit of deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) which contains a nitrogenous base. Also, portion of the nucleotide include:

A nitrogenous base.A phosphate group.Deoxyribose sugar (5-carbon sugar).

Based on scientific research and records, the portion of the nucleotide in which ddNTPs (ddGTP, ddATP, ddTTP and ddCTP) and deoxynucleoside triphosphate (dNTPs) differ is known as deoxyribose sugar.

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A broker sold a property for the list price. Despite the fact the broker had a valid listing, the broker was NOT entitled to a commission because the listing

Answers

Even though the broker had a valid listing, the broker wasn't entitled to a commission because the listing was a: b. net listing.

What is an open listing?

An open listing can be defined as a property sale which avails multiple real estate brokers an option to market and sell, so as enable them earn commission on the sale of any property such as a home.

In this scenario, we can infer and logically deduce that the broker wasn't entitled to a commission because the listing was a net listing, even though he or she had a valid listing.

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Complete Question:

A broker sold a property for the list price. Despite the fact the broker had a valid listing, the broker was NOT entitled to a commission because the listing was a

a. open listing.

b. net listing.

c. exclusive agency listing.

d. exclusive right-to-sell listing.

Classify each of the following as a pure substance, homogeneous mixture, solution, or colloid.

Answers

Acetic acid and ether are pure substance because they can not be further broken down.

What is a homogeneous mixture?

A homogenous mixture consists only of single phase. A solution is comprised of a solute and a solvent while a colloid is a false solution.

The following is a classification of each of the items;

1- Acetic acid - pure substance

2- Ether - pure substance

3- Vinegar - homogeneous mixture

4- Gravy - colloid

5- Beef stew - colloid

6- Seltzer water - solution

7- Salad - colloid

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Mising parts;

Classify each of the following as a pure substance, homogeneous mixture, solution, or colloid.

1- Acetic acid

2- Ether

3- Vinegar

4- Gravy

5- Beef stew

6- Seltzer water

7- Salad

Which of the following descriptions most accurately portrays emergency medical services (EMS)

Answers

The  descriptions that most accurately portrays emergency medical services is: team of health care professionals who provide emergency care and transportation to the sick and injured.

What is emergency medical service?

Emergency medical services can be defined as the way of providing urgent medical assistance to victims  incase of unforeseen  circumstance.

Hence, a team  or member of health care professionals whose sole responsibility is to provide emergency care and transportation to the sick and injured most accurately  portrays emergency medical services.

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can catfish be both fresh water and salt water

Answers

Answer: depending on what water they were dreaded from

Explanation:

what math is needed for theoretical physics

Answers

Answer: Abstract Algebra, Lie Groups/Algebras, Topology, Complex Analysis and Differential Geometry.

Explanation:

Those are the maths needed

To do theoretical physics, you're gonna need to know at least Abstract Algebra, Lie Groups/Algebras, Topology, Complex Analysis and Differential Geometry.

Which best describes the tempo of this excerpt

Answers

The tempo of the excerpt can best be described as Adagio.

What is an adagio tempo?

This refers to when the tempo of a musical piece is done slowly or rather in slow time.

This enables for powerful music as it feels like every part of the musical piece by Maria Szymanowska is heard individually.

Rest of the question talks about an excerpt from a music piece by Maria Szymanowska.

The music piece is a Mozart Piano Concerto.

Options for this question are:

FortelargoAdagioAllegro

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What were the two rules ALL of the Italian states agreed upon prior to the invasion of Charles

Answers

The two rules that all of the Italian states agreed to are:

that no armed foreigner should be allowed invasion of the  Italian nation.that no one of their own number should be suffered in order for their to be territory expansion.

What is the unification of Italy?

This was the movement that took place in Italy. As a result of this movement, there came to be a consolidation of the states of Italy to become a particular state.

The unification was the consolidation of the Italian Peninsula in top a particular kingdom. This was known to have take place in  the nineteenth century. It ended as at the same time that the Unification of Germany was taking place in the year 1871.

Hence the rules are to prevent invasions of foreigners and to prevent territorial expansion.

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Which of the following is an advantage of seniority pay systems?

Answers

Here they reward employees on an objective basis.

Objective-based rewards system

In an objective-based rewards system, compensation is given to employees to achieve an objective, which could be to simply boost their performance, encourage employees to follow work ethics like being honest, etc.

For example, a company wanting to boost sales may decide to introduce a commission for each unit sold. The commission introduced is an example of an objective-based rewards system.

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How many pieces of data are represented in the histogram?

Answers

The number of data are represented in the histogram is 37. See the explanation for same below.

How do you compute the number of pieces of data form a histogram?

The Bin size is given as the difference between two consecutive lower and upper limits

Thus, the number of pieces of data are:

=2+6+5+7+8+9

=37

What is a histogram?

A diagram with rectangles whose width is equal to the class interval and whose size is related to the frequency of a variable is called a histogram.

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37 cos(x2) dx 0 Do the following. (a) Find the approximations T8 and M8 for the given integral. (Round your answer to six decimal places.)

Answers

The approximations T8 and M8 for the given integral are:

T8 = 33.386321; andM8 = 33.50794

What is an integral?

An Integral is a variable of which a given function is the derivative, i.e. it gives that function when differentiated and may express the area under the curve of the function's graph.

What is the explanation to above answer?

Given:

F(x) = 37 cox (x²)

Internal = [0,1] n = 8 in Δ x = 1/8

The sub intervals are:

[0, 1/8], [1/8, 2/8], [2/8, 3/8], [ 3/8, 4/8], [ 4/8, 5/8], [ 5/8, 6/8], [6/8, 7/8], [ 7/8, 1]

The mid points are given as:

1/16, 3/16, 5/16, 7/16, 9/16, 11/16, 13/16, 15/16

and X₀ = 0, X₁ = 1/8, X₂ = 2/8

Using the Trapezium Rule which states that:

[tex]\int\limits^1_0 cos(x)^{2} } \, dx[/tex] = Δx/2 [tex][f(xo) + 2f(x1) 2f(x2) + ....+ 2f(x7) + f(x8)][/tex]

= 1/1Q[f(0) + 2f (1/8) + 2f(2/8) + ....+ 2f(7/8) + f(1)]

= 0.902333

Now

T8 = [tex]\int\limits^1_0 {37Cos(x)^{2} } \, dx[/tex]

= [tex]37\int\limits^1_0 {(0.902333)} } \, dx[/tex]

= 37 (0.902333)

T8 = 33.386321

It is to be noted that the midpoints rule is given as;

[tex]\int\limits^1_0 {Cos(x)^{2} } \, dx[/tex]  = Δx [f(1/16) + (3/16) + .... + f(15/16)]

= 1/8[f(1/16) + f (3/16) + f(5/16) + f(7/16) + f(9/16) + f(11/16) + f(13/16) + f(15/16)]

= 0.905620

From the above,

M8 = [tex]\int\limits^1_0 {37 Cos(x)^{2} } \, dx[/tex]

= [tex]37\int\limits^1_0 {Cos(x)^{2} } \, dx[/tex]

= 37 (0.905620)

M8 = 33.50794

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Porter's five competitive forces form a model for ______ analysis.

Answers

Porter's five competitive forces form a model for a company's competitive environment analysis.

What is a Competitive Force?

This refers to the different entities that are direct or indirect rivals to a particular business and this is shown through their price aggregation, differentiation, etc.

Hence, we can see that based on the five competitive forces by Porter, they act as a model or framework for a company's competitive environment analysis.

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Answer:industry

Explanation:

I did the test

two adjacent sides of a parallelogram are 29 and 37

Answers

By applying the law of cosine, the length of c is approximately equal to 56 meters.

How to determine the length of c?

In order to determine the length of c, we would apply the law of cosine:

C² = A² + D² - 2(A)(D)cosD

Note: Angle D = 180 - 65 = 115°

Substituting the given parameters into the formula, we have;

C² = 37² + 29² - 2(37)(29)cos115

C² = 1,369 + 841 - 2146(-0.4226)

C² = 2210 + 906.94

C² = 3116.94

C = √3116.94

C = 55.83 56 meters.

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Complete Question:

Two adjacent sides of a parallelogram are 27' and 37', respectively. The angle (between these two sides is 65°). Find the length of c.

Answer:55.8 the answer is for acellus

Explanation:

Many health authorities encourage Americans to include more plant sources of protein in their dietary patterns. From the following options, click to select three potential health benefits associated with choosing plant sources of protein in place of animal sources of protein.

Answers

Plant-based proteins are beneficial as they:

provide higher intake of fiber, lower risk of cardiovascular disease due to low no saturated fatshelp in weight loss

What are potential health benefits associated with choosing plant sources of protein in place of animal sources of protein?

Proteins are essential to building healthy bodies and repair of tissues.

Plant-based proteins have been shown to provide the following benefits:

higher intake of fiber, lower risk of cardiovascular disease due to low no saturated fatshelps in weight loss

In conclusion, plant protein sources provide health benefits.

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This type of hormone characteristically requires a second messenger.

Answers

The type of hormone that characteristically requires a second messenger is: "Water Soluble Hormone" (Option C)

What is the function of a second messenger hormones?

Second messengers bridge the gap between signaling chemicals including neurotransmitters, cytokines, and growth factors and changes.

in gene expression, which are ultimately responsible for nerve cell proliferation, differentiation, and maturation.

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Full Question:

This type of hormone characteristically requires a second messenger.

A) lipid-soluble

B) steroid

C) water-soluble

D) prostaglandin

the concept of time value money is important to financial decision making because

Answers

The concept of time value of money is very important and essential to financial decision-making because: D) all of these.

What is money?

Money is any formally recognized economic unit that's universally accepted as a medium of exchange for goods and services, as well as repayment of debts such as loans, taxes across the world.

What is time value of money?

Time value of money can be defined as a measure of the difference in values of money in comparison to when it is received.

In conclusion, we can infer and logically deduce that the concept of time value of money is very important and essential to financial decision-making because it emphasizes earning a return of interest on investment and it applies to future cash flows.

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Complete Question:

The concept of time value of money is important to financial decision making because?

A) it emphasizes earning a return of interest on the money you invested.

B) it recognizes that $1 today has more value than $1 received a year from now

C) it can be applied to future cash flows in order to compare different streams of income.

D) all of these.

A programmer intended to compute (a AND b) OR c, and wrote the following code, which sometimes yields incorrect output. Why

Answers

A programmer intended to compute (a AND b) OR c, and wrote the following code, which sometimes yields incorrect output. The reason for this is because:

AND and OR are logical operators that operate on Boolean expressions to return true or false results.However, | and & are bitwise operators that act on a given number's binary digits bit by bit and yield a new number after the operation.

Who is a computer programmer?

A computer programmer is a person who specializes in creating codes with which a computer is instructed to achieve a specific and expected output.

What are the other reasons for the inconsistent yield or output?

The program attempts to calculate (a AND b) OR c using the logical operators AND and OR, which will return either 1 (True) or 0 (False) depending on the inputs.

However, in the program, the programmer used the bitwise or(|) and bitwise and(&) operators: c | (a & b), which returns a new number depending on the values of a, b, and c.

As a result, it will produce the right outcome only when the logical AND - OR operation and bitwise and - or on inputs a, b, and c produce either 0 or 1. Otherwise, the outcome will be inaccurate.

As a result, the right response is that bitwise operators should be substituted by logical operators.

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In anticipation of receiving a fertilized ovum, the lining of the uterine wall

Answers

Every month, the lining of the uterus becomes thicker in preparation for an egg that has been fertilized to place itself there. In the event that this transpires, hormones originating from the reproductive organs will stabilize the vascular tissue of the endometrium, which in turn will offer a setting for the embryo to grow in.

This is further explained below.

What is the uterine wall?

Generally, The uterine lining grows every month in anticipation of the implantation of a fertilized ovum. When this happens, the endometrium's vascular tissue is stabilized by hormones from the reproductive organs, providing an environment for the growing fetus.

In conclusion, There are three distinct layers of muscle tissue that compose the uterine wall. The muscle fibers are intertwined with the connective tissue of blood vessels, elastic fibers, and collagen fibers, and they may run in either of three directions: longitudinally, circularly, and obliquely. As the baby grows within the uterus, this thick muscular wall begins to stretch out and eventually becomes much thinner.

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A coworker performs a large favor for you. Based on ________, you will now feel obligated to do a favor for them. Group of answer choices the norm of indifference the norm of reciprocity the coworker’s charisma zones of indifference

Answers

Based on the norm of reciprocity, you will feel obligated to do a favor for a coworker when he or she performs a large favor for you.

What is the norm of reciprocity?

The norm of reciprocity can be defined as a social convention requires that a person repay in kind a favor or assistance that was done to them, especially to the performer of such act.

Based on the norm of reciprocity, we can infer and logically deduce that you will feel obligated to do a favor for a coworker when he or she performs a large favor for you.

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Hotels charge a higher price for rooms with a nicer view, such as a skyline view or a coastal view. Assume that all consumers receive a higher utility when staying in a room with a nicer view.

Answers

"Hotels charge a higher price for rooms with a nicer view, such as a skyline view or a coastal view."There is no price discrimination. This is further explained below.

What is price discrimination.?

Generally, the practice of selling one and the same product to several customers at a variety of price points, with the goal of increasing overall sales and profits.

In conclusion, if there are different prices for the same product. A hotel room with a beautiful view is a distinct good from a conventional hotel room. As a consequence, the price discrepancy is due only to differences in the GOOD's QUALITY, and not to price discrimination.

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Juan, a network user, sends an email to you, the IT admin of the network, stating that his account is locked because he has lost his password. Select all appropriate steps in helping Juan resolve his situation. Check all that apply.

Answers

Appropriate steps that can help Juan resolve his situation are:

Make sure the password reset is authorizedIssue a temp password/ check The user must change the password at the next login

What are the steps that can help Juan?

The IT administrator can confirm the authenticity of a password reset option. Next, a temporary password will be issued to the user and this will be changed when next he or she logs in.

All of these steps are geared at ensuring the protection of data.

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Which school of thinking in psychology includes the following concepts: figure-ground relationship, law of continuity, and principle of closure

Answers

The concepts of figure-ground relationship, law of continuity, and principle of closure is Gestalt principles.

What is Gestalt principles?

Gestalt principles is a school of thought in psychology that involves figure-ground relationship, grouping by proximity or similarity, law of continuity, and closure are all used to help explain how we organize sensory information.

Thus,  the concepts of figure-ground relationship, law of continuity, and principle of closure is Gestalt principles.

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IMT-2020 represents the next generation of cellular capability termed 5G.

Answers

The statement that IMT-2020 represents the next generation of cellular capability termed 5G is:

True

What is IMT -2020?

IMT 2020 is a term that was assigned to all 5G networks by the International Telecommunications Union.

The term itself stands for International Mobile Telecommunications. This term stands for the policy that network adopters will have to employ. It was framed up in the year, 2020 and contains vital information that all network holders who want to adopt the 5G network system must use.

Failure to abide by the guiding policy might cause a withdrawal from the right to administrate a complex system like the 5G network. So, we can conclude that the information about the IMT-20 stated above is correct.

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your is a number assigned to you that helps a lender judge your ability to repay a loan brainly

Answers

Credit score is a number assigned to you that helps a lender judge your ability to repay a loan.

What is credit score?

Credit score is used to determine the ability  of a borrower to payback a loan.

Credits score is important as it help to measure the capacity of a borrower to pay back the money lend to him /her based on their past credit score record.

Based on this most loan companies tend to make use of credit score by checking and verifying a borrower credit score before giving out a loan to a borrower as this score will help them to know if the borrower will payback or not.

Therefore, when borrower has a high credit score their is likelihood or tendency that the borrower will pay back the loan .

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. How did Anglo-American settlers in Texas see themselves

Answers

The Anglo-American settlers in Texas saw themselves as Americans who happened to be in Mexican territory.

How did Anglo-Americans behave in Texas?

Anglo-Americans in Texas when it was under the control of Mexico, did not believe that they were under the Mexican government and did not follow Mexican culture.

They instead believed that the laws of the United States still applied to them, which was why they used enslaved people even though Mexico had outlawed this.

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Assuming that everything else is equal, a U.S. government bond that matures 30 years from now most likely pays alower interest rate than a U.S. government bond that matures 10 years from now.

Answers

Assuming that everything else is equal, a U.S. government bond that matures 30 years from now most likely pays a higher interest rate than a U.S. government bond that matures 10 years from now. This is further explained below.

What is the interest rate?

Generally, The Federal Reserve raised its benchmark interest rate by 0.75 percentage points on Wednesday, bringing the total to a range of 2.25 percent to 2.5 percent. This is the second straight rise in interest rates by the Federal Reserve. Chair Jerome Powell has indicated that there will come a time when the Fed would begin to pause rises in order to evaluate the effect of those hikes.

In conclusion, When all other factors are considered, a United States government bond with a maturity date that is 30 years in the future will almost certainly pay a greater interest rate than a United States government bond with a maturity date that is 10 years in the future.

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Please select the word from the list that best fits the definition Emilio put on the shirt.

Answers

The word that best fits the sentence Emilio put on the shirt is Emilio se pone la camisa in Spanish.

What is the sentence about?

This is a sentence that is asking the person that is being spoken to to perform an action.

We have to pick the right word as it is written in Spanish. The rights sentence is  Emilio se pone la camisa.

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Other Questions
True or false: one reason for the growth of sponsorships has been the need for companies to break through the clutter of advertising. Which of the following are potential consequences when someone develops a pattern of not accepting personal responsibility? (i) Increased self esteem and pride (ii) Overdependence on others for a sense of self worth (iii) Successful relationships with friends and family members A. i only B. ii only C. iii only D. i, ii, and iii Please select the best answer from the choices provided A B C D Lauren's mother is taking brownies out of the oven. which would suggest most strongly that the id is firmly in control of lauren's behavior? Question 4 of 10What did Giotto introduce into paintings of religious scenes?A. Figures that were not divineB. Materialistic grandeurC. Emotional intensityD. Depictions of evil What is 125x + 64y2 written as a sum of cubes?O (25x3)3 + (44)3O (5x)3 + (164)O (25x)3 + (8y4)3 (5x3)3 + (4y4)3 Write the equation of the line through the points (1,3) & (-2,5)in slope-intercept form Ecological balance is the goal that assumes the global economy can achieve balanced economic conditions ___________________ . Which one of the following is the most widely used source of short-term funding that Mr. Boyd (and other small business owners) would use to operate their business A cube with an edge of 10cm is filled with water.How much can it contain? What type of muscular assessment is the bench press test? Muscular strength assessment Muscular size assessment Muscular endurance assessment Muscular metabolic assessment 3 = x+3 5x how can I solve this using a multi step equation The period of a satellite, the time it takes for a complete revolution, depends on the satellite's: _________ How do I find and construct the geometric mean in this problem? Identify two concepts from research or ebp that you intend to apply to your nursing practice and why Lithified ash (or ash mixed with pyroclastic fragments) forms a volcaniclastic rock called a:________ Explain why Rolle's Theorem does not apply to the function even though there exist a and b such that f(a) What program is available to support c-snp and d-snp members who may have unique health care needs?. Question 3(Multiple Choice Worth 2 points)(09.03 MC)Read the excerpt from the story Animals in the Zoo."Don't worry, we won't be operating on the tamarins today. We are just checking their health and looking at their eyes, ears, and hands during this visit. We want to make sure they are healthy enough to be put into their enclosure," she said. Just then, a zoo employee brought in the two tamarins, and Ryan immediately understood why they were called cotton-top tamarins. Each of them had a white tuft of hair on top of their head. The zoo employee told Ryan and his mom that these two tamarins were the first of many to come to the zoo. If these two stayed healthy and appeared to be happy in their enclosure, the zoo would be able to get even more tamarins to fill the exhibit which is why they wanted to make sure they had an expert come in to examine them.It took Ryan's mother 30 minutes to check each tamarin. She wanted to make sure they both had thorough examinations. Finally, after an hour, she gave them both the all clear.One of the tamarins was looking right at Ryan and had her arms stretched out. Ryan looked at his mom with an inquiring gaze. She nodded at him, so he reached out and picked her up from the examination table. The tamarin licked the end of his nose, and Ryan laughed. He definitely would be back to visit the tamarins as soon as he could.Which line from the excerpt best supports the idea that Ryan is an animal-lover?A. She wanted to make sure they both had thorough examinations.B. One of the tamarins was looking right at Ryan and had her arms stretched out.C. She nodded at him, so he reached out and picked her up from the examination table.D. He definitely would be back to visit the tamarins as soon as he could. Mrs. jones has been throwing up for several days, unable to eat or drink. you find her in bed. she is pale, lethargic, and her eyes are dull. she is likely suffering from:_______ Using Your Sense to Visualize the PoemThough I am old with wanderingThrough hollow lands and hilly lands,I will find out where she has gone,And kiss her lips and take her hands;And walk among long dappled grass,And pluck till time and times are done,The silver apples of the moon,The golden apples of the sun.-"The Song of Wandering Aengus,"William Butler YeatsWhich best describes an image of Aengus based onthe first two lines of this stanza?O Aengus looks unhappy, because he has not foundthe girl.O Aengus looks tired and can no longer climb up anddown.Aengus looks old from walking everywhere.Aengus looks worn out from climbing up and downmountains.